Challenges in ESI-MS-based Untargeted Metabolomics
نویسندگان
چکیده
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic changes taking place in biological systems under different conditions. In this article, we aim to provide short overview of the liquid-phase separation methods hyphenated MS perform untargeted samples. Each approach complemented by up-to-date literature guide readers, well practical information avoiding or fixing some most frequently encountered pitfalls. This article covers mainly data acquisition, but discussion provided regarding signal processing and treatment, analysis its interpretation context metabolomic studies.
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ژورنال
عنوان ژورنال: Chimia
سال: 2022
ISSN: ['0009-4293', '2673-2424']
DOI: https://doi.org/10.2533/chimia.2022.90